Advances in Modelling and Clinical Application of - download pdf or read online

By Frank H. M. Engbers (auth.), Jaap Vuyk, Stefan Schraag (eds.)

ISBN-10: 1441991921

ISBN-13: 9781441991928

ISBN-10: 1461348307

ISBN-13: 9781461348306

Since its release in 1998 the eu Society for Intravenous Anaesthesia (EuroSIVA) has come far in delivering academic fabric and aiding the learn and scientific software of intravenous anaesthesia. After the 1st annual conferences held in Barcelona and Amsterdam in 1998 and 1999, 3 different winning conferences happened in Vienna, Gothenburg and great in 2000, 2001 and 2002. subsequent to those major conferences, beginning within the yr 2000, a smaller wintry weather assembly has been organised each final week of January in Crans Montana, Switzerland. either the most summer time and the wintry weather conferences breathe an analogous surroundings of sharing the most recent on intravenous anaesthesia study within the presence of a pleasant setting and sturdy corporation. because the first conferences the academic instruments of EuroSIVA have elevated in volume and technical caliber permitting electronic slide and video presentation in addition to using the pc simulation software TIVAtrainer throughout the speaker periods and the workshops. additionally, EuroSIVA now exploits an internet site www. eurosiva. org that enables for non-stop trade of data on intravenous anaesthesia, the TIVAtrainer, the EuroSIVA conferences and on-line registration for those conferences. The EuroSIVA is presently engaged in pleasant contacts with the Asian Oceanic Society for Intravenous Anaesthesia (AOSIVA), the uk Society for Intravenous Anaesthesia (UKSIVA), the Korean Society for Intravenous Anaesthesia (KSIVA), the eu Society of Anaesthesiology (ESA) and the foreign Society for utilized Pharmacology (ISAP).

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Extra info for Advances in Modelling and Clinical Application of Intravenous Anaesthesia

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P. Kampine, First pass uptake of fentanyl, meperidine, and morphine in the human lung, Anesthesiology 67, 466-472 (1987). 11. F. Boer, J. G. Bovill. A. G. Burm, and R. A. Mooren, Uptake of sufentanil, alfentanil and morphine in the lungs of patients about to undergo coronary artery surgery, Br. J. Anaesth. 68,370-375 (1992). 12. Y. L. He, H. Ueyama, C. Tashiro, T. Mashimo, and I. Yoshiya, Pulmonary disposition of propofol in surgical patients, Anesthesiology 93, 986-991 (2000). 13. 1. A. Kuipers, F.

8 ~ OJ ~ 0 ! ,. > ~ Figure 4. A response surface between drug A and B. 3. The Optimal Response In many experimental situations, response surfaces are used to determine optimal response conditions. Although the optimal conditions are readily determined from Figure 2 (the highest point), these are not so easily determined in Figure 4. Either drug alone or any ratio of the two drugs is capable of achieving the maximum effect (if this is the goal). Furthermore, in general the optimum cannot be determined without considering the pharmacokinetic and side effect profiles of the individual drugs.

2. J. A. Kuipers. F. Boer, A. de Roode, E. Olofsen. J. G. Bovill. and A. G. Burm. Modeling population pharmacokinetics of lidocaine: should cardiac output be included as a patient factor? Anesthesiology 94. 566-573 (2001). 3. T. K. Henthorn. T. C. Krejcie. and M. J. Avram, The relationship between alfentanil distribution kinetics and cardiac output. Clin. Pharmacol. Ther. 52, 190-196 (1992). 4. G. L. Ludbrook and R. N. Upton. A physiological model of induction of anaesthesia with propofol in sheep.

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Advances in Modelling and Clinical Application of Intravenous Anaesthesia by Frank H. M. Engbers (auth.), Jaap Vuyk, Stefan Schraag (eds.)

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